Renger, John J. : rechercher sur Z-Library

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1

The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia

Coleman, Paul J., Gotter, Anthony L., Herring, W. Joseph, Winrow, Christopher J., Renger, John J.

Journal:

Annual Review of Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 2.40 MB

english, 2017

2

Early modelling results from the SESAME and ASHOE campaigns

Pyle, John A., Chipperfield, Martyn P., Kilbane-Dawe, Iarla, Lee, Adrian M., Stimpfle, Richard M., Kohn, Daniel, Renger, Wolfgang, Waters, Joe W.

Journal:

Faraday Discussions

Année:

1995

Langue:

english

Fichier:

PDF, 2.98 MB

english, 1995

3

Experimental validation of an ATM traffic control framework in the EXPLOIT testbed

Thomas Renger, Egil Aarstad, Harald Pettersen, John Kroeze

Journal:

Transactions on Emerging Telecommunications Technologies

Année:

1996

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1996

4

Tricyclic imidazole antagonists of the Neuropeptide S Receptor

B. Wesley Trotter, Kausik K. Nanda, Peter J. Manley, Victor N. Uebele, Cindra L. Condra, Anthony L. Gotter, Karsten Menzel, Martin Henault, Rino Stocco, John J. Renger, George D. Hartman, Mark T. Bilo

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1011 KB

english, 2010

5

Conformational analysis of N,N-disubstituted-1,4-diazepane orexin receptor antagonists and implications for receptor binding

Christopher D. Cox, Georgia B. McGaughey, Michael J. Bogusky, David B. Whitman, Richard G. Ball, Christopher J. Winrow, John J. Renger, Paul J. Coleman

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 534 KB

english, 2009

6

Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats

Sokreine Suon, Jie Zhao, Stephanie A Villarreal, Nikesh Anumula, Mali Liu, Linda M Carangia, John J Renger, Celina V Zerbinatti

Journal:

Molecular Neurodegeneration

Année:

2010

Langue:

english

Fichier:

PDF, 4.61 MB

english, 2010

7

Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers

Lynette M. James, Robert Iannone, John Palcza, John J. Renger, Nicole Calder, Kristine Cerchio, Keith Gottesdiener, Richard Hargreaves, M. Gail Murphy, Julia Boyle, Derk-Jan Dijk

Journal:

Psychopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 477 KB

english, 2011

8

Additive effects of a cholinesterase inhibitor and a histamine inverse agonist on scopolamine deficits in humans

William Cho, Paul Maruff, John Connell, Cindy Gargano, Nicole Calder, Scott Doran, Sabrina Fox-Bosetti, Aizza Hassan, John Renger, Gary Herman, Christopher Lines, Ajay Verma

Journal:

Psychopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 285 KB

english, 2011

9

10.1038/73921

Jaenisch, Rudolf, Fan, Guoping, Egles, Christophe, Sun, Yi, Minichiello, Liliana, Renger, John J., Klein, Rüdiger, Liu, Guosong

Journal:

Nature Neuroscience

Année:

2000

Langue:

english

Fichier:

PDF, 689 KB

english, 2000

10

Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses

Huang, Zhuo, Lujan, Rafael, Kadurin, Ivan, Uebele, Victor N, Renger, John J, Dolphin, Annette C, Shah, Mala M

Journal:

Nature Neuroscience

Année:

2011

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2011

11

Control of firing patterns through modulation of axon initial segment T-type calcium channels

Kevin J. Bender, Victor N. Uebele, John J. Renger, Laurence O. Trussell

Journal:

The Journal of Physiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2012

12

Switching block studies, network performance evaluation and traffic engineering for ATM

Jordi Domingo, Herman Michiel, Reinhard Haberman, Matthias Sommer, Nikolas Mitrou, Yonggang Du, Martina Götz, Ralf Lehnert, Zhili Sun, John P. Cosmas, Thomas Renger, Thomas Theimer

Journal:

Transactions on Emerging Telecommunications Technologies

Année:

1994

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1994

13

Sub-chronic administration of zolpidem affects modifications to rat sleep architecture

John J Renger, Susan L Dunn, Sherri L Motzel, Colena Johnson, Kenneth S Koblan

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 558 KB

english, 2004

14

Refined anatomical isolation of functional sleep circuits exhibits distinctive regional and circadian gene transcriptional profiles

Christopher J. Winrow, Keith Q. Tanis, Alison M. Rigby, Rhonda R. Taylor, Kyle Serikawa, Mollie McWhorter, George Y. Tokiwa, Matthew J. Marton, David J. Stone, Kenneth S. Koblan, John J. Renger

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 3.41 MB

english, 2009

15

26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: Evidence-based nutrition

Hans Konrad Biesalski, Peter J. Aggett, Robert Anton, Paul S. Bernstein, Jeffrey Blumberg, Robert P. Heaney, Jeya Henry, John M. Nolan, David P. Richardson, Ben van Ommen, Renger F. Witkamp, Ger T. Ri

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2011

16

Role of voltage-gated calcium channels in potassium-stimulated aldosterone secretion from rat adrenal zona glomerulosa cells

Victor N. Uebele, Cindy E. Nuss, John J. Renger, Thomas M. Connolly

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 339 KB

english, 2004

17

Trazodone inhibits T-type calcium channels

Richard L. Kraus, Yuxing Li, Aneta Jovanovska, John J. Renger

Journal:

Neuropharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 735 KB

english, 2007

18

Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane

Veit-Simon Eckle, Michael R. DiGruccio, Victor N. Uebele, John J. Renger, Slobodan M. Todorovic

Journal:

Neuropharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 726 KB

english, 2012

19

A Developmental Switch in Neurotransmitter Flux Enhances Synaptic Efficacy by Affecting AMPA Receptor Activation

John J Renger, Christophe Egles, Guosong Liu

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2001

20

State-dependent properties of a new T-type calcium channel blocker enhance CaV3.2 selectivity and support analgesic effects

Francois, Amaury, Kerckhove, Nicolas, Meleine, Mathieu, Alloui, Abdelkrim, Barrere, Christian, Gelot, Agathe, Uebele, Victor N., Renger, John J., Eschalier, Alain, Ardid, Denis, Bourinet, Emmanuel

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 900 KB

english, 2013

21

A novel multivalent Abeta peptide vaccine with preclinical evidence of a central immune response that generates antisera recognizing a wide range of Abeta peptide species

Mary J. Savage, Guoxin Wu, Alexander McCampbell, Keith R. Wessner, Michael Citron, Xiaoping Liang, Sidney Hsieh, Abigail L. Wolfe, Gene G. Kinney, Laura B. Rosen, John J. Renger

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 40 KB

english, 2010

22

Anti-Aβ antibody m266 penetrates the blood-brain barrier but does not reduce the deposition of plaque in a mouse model of Alzheimer's disease

Paul Shughrue, Renee Gaspar, Stephanie Villarreal, Paul McQuade, Wei-Qin Zhao, Abigail Wolfe, Lingyi Huang, Fubao Wang, John Renger

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 64 KB

english, 2010

23

Development of a rodent-specific ELISA and delipidation method for accurate measurement of apoE levels in the CSF

Jill Maxwell, Sokreine Suon, Peter Lemaire, Mary Savage, Celina Zerbinatti, John Renger, Zhenhua Wu

Journal:

Alzheimer's & Dementia

Année:

2011

Langue:

english

Fichier:

PDF, 54 KB

english, 2011

24

A quantitative assay selective for amyloid oligomer species differentiates cerebrospinal fluid from Alzheimer's disease and age-matched normal

Abigail Wolfe, Alexander McCampbell, Nate Hatcher, Katherine Tugusheva, Sharie Haugabook, Jill Maxwell, Guoxin Wu, Bonnie Howell, John Renger, Paul Shughrue, Mary Savage

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 57 KB

english, 2012

25

Concomitant alterations of physiological and developmental plasticity in drosophila CaM kinase II-inhibited synapses

Jing Wang, John I. Renger, Leslie C. Griffith, Ralph J. Greenspan, Chun-Fang Wu

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1994

26

T-Type Calcium Channel Antagonism Decreases Motivation for Nicotine and Blocks Nicotine- and Cue-Induced Reinstatement for a Response Previously Reinforced with Nicotine

Jason M. Uslaner, Joshua D. Vardigan, Jason M. Drott, Victor N. Uebele, John J. Renger, Ariel Lee, Zhaoxia Li, A.D. Lê, Pete H. Hutson

Journal:

Biological Psychiatry

Année:

2010

Langue:

english

Fichier:

PDF, 419 KB

english, 2010

27

Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia

Raheem, Izzat T., Breslin, Michael J., Fandozzi, Christine, Fuerst, Joy, Hill, Nicole, Huszar, Sarah, Kandebo, Monika, Kim, Somang H., Ma, Bennett, McGaughey, Georgia, Renger, John J., Schreier, John

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 797 KB

english, 2012

28

A novel link between clusterin and tau pathology in Alzheimer's disease

Hayashi, Ikuo, Wong, Jacky, Tugusheva, Kate, Marcus, Jacob, Wang, Xiaohai, Tanis, Keith, Renger, John, Zerbinatti, Celina

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 53 KB

english, 2013

29

P4-332: In vivo pharmacodynamic effects of BQCA, a novel selective allosteric M1 receptor modulator

Wittmann, Marion, Xu, Guangping, Pearson, Michelle, Garson, Susan, Doran, Scott, Renger, John J., Danziger, Andrew, Regan, Christopher P., Seabrook, Guy R., Ray, William J.

Journal:

Alzheimer's & Dementia

Année:

2008

Langue:

english

Fichier:

PDF, 54 KB

english, 2008

30

Novel Blockers of T-Type Calcium Channels Modify Gating

Bergson, Pamela, Uebele, Victor N., Renger, John J., Hanck, Dorothy A.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 42 KB

english, 2011

31

Community partnership to promote home fire safety in children with special needs

Lehna, Carlee, Janes, Erika G., Rengers, Sharon, Graviss, Jackie, Scrivener, Drane, Knabel, Tom, Carver, Elizabeth, Myers, John

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 264 KB

english, 2014

32

Expression of the cholesterol ester protein CETP in amyloid precursor protein transgenic mice impacts brain cholesterol and amyloid levels

Cramer, Paige, Li, Zhihua, Rosahl, Thomas, Renger, John, Zerbinatti, Celina

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 112 KB

english, 2013

33

Effects of elevated plasma cholesterol on CSF lipids and Alzheimer's disease CSF biomarkers in African green monkeys

Hayashi, Ikuo, Hayashi, Ikuo, Tugusheva, Katherine, Szczerba, Peter, Hasselschwert, Dana, Petrose, Phyllis, Goetzmann, Jason, Renger, John, Zerbinatti, Celina

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 50 KB

english, 2012

34

Selective orexin 2 receptor antagonism blocks cue-induced reinstatement, but not nicotine self-administration or nicotine-induced reinstatement

Uslaner, Jason M., Winrow, Christopher J., Gotter, Anthony L., Roecker, Anthony J., Coleman, Paul J., Hutson, Pete H., Le, Anh D., Renger, John J.

Journal:

Behavioural Brain Research

Année:

2014

Langue:

english

Fichier:

PDF, 560 KB

english, 2014

35

Cholesterol ester transfer protein–deficient polymorphisms alter cerebrospinal fluid biomarkers and reduce Alzheimer's disease–related cognitive impairment in apolipoprotein E-ε4 carriers

Hayashi, Ikuo, Wong, Jacky, Tugusheva, Katherine, Hargreaves, Richard, Renger, John, Zerbinatti, Celina

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 232 KB

english, 2012

36

ApoE4 confers better spatial memory than apoE3 in young adult hAPP-Yac/apoE-TR mice

Moreau, Pierre-Henri, Bott, Jean-Bastien, Zerbinatti, Celina, Renger, John Joseph, Kelche, Christian, Cassel, Jean-Christophe, Mathis, Chantal

Journal:

Behavioural Brain Research

Année:

2013

Langue:

english

Fichier:

PDF, 406 KB

english, 2013

37

Novel Blockers of T-type Calcium Channels Modify Gating

Bergson, Pamela, Hu, Tiffany, Uebele, Victor N., Renger, John J., Hanck, Dorothy A.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 282 KB

english, 2010

38

Orexin receptor antagonists: a review of promising compounds patented since 2006

Coleman, Paul J, Renger, John J

Journal:

Expert Opinion on Therapeutic Patents

Année:

2010

Langue:

english

Fichier:

PDF, 507 KB

english, 2010

39

Preface to the Special Issue “Novel Pharmaconeurogenetic Approaches Arising from Progress in Translational Genetics”

Renger, John J., Kern, Jonathan T.

Journal:

Journal of Neurogenetics

Année:

2011

Langue:

english

Fichier:

PDF, 104 KB

english, 2011

40

Comparison of conventional immunoassays and the oestrogen radioreceptor assay for screening for the presence of oestrogenic anabolic compounds in urine samples†

Arts, Cor J. M., van Baak, Martin J., van de Velde-Fase, Kitty, Witkamp, Renger F., Elliot, Christopher J., Armstrong Hewitt, S., Cooper, John

Journal:

The Analyst (Royal Society of Chemistry)

Année:

1998

Langue:

english

Fichier:

PDF, 51 KB

english, 1998

41

Evidence for orexinergic mechanisms in migraine

Hoffmann, Jan, Supronsinchai, Weera, Akerman, Simon, Andreou, Anna P., Winrow, Christopher J., Renger, John, Hargreaves, Richard, Goadsby, Peter J.

Journal:

Neurobiology of Disease

Année:

2015

Langue:

english

Fichier:

PDF, 682 KB

english, 2015

42

Improved cognition without adverse effects: novel M1 muscarinic potentiator compares favorably to donepezil and xanomeline in rhesus monkey

Vardigan, Joshua D., Cannon, Christopher E., Puri, Vanita, Dancho, Mandy, Koser, AmyJo, Wittmann, Marion, Kuduk, Scott D., Renger, John J., Uslaner, Jason M.

Journal:

Psychopharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 512 KB

english, 2015

43

Early-stage comparative effectiveness: Randomized controlled trial with histamine inverse agonist MK-7288 in excessive daytime sleepiness patients

Sun, Hong, MacLeod, Catherine, Mostoller, Kate, Mahon, Chantal, Han, Lingling, Renger, John J., Ma, Junshui, Brown, Kevin R., Schulz, Valerie, Kay, Gary G., Herring, W. Joseph, Lines, Christopher, Ros

Journal:

Journal of Clinical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 414 KB

english, 2013

44

Impact of Children With Special Needs on Differences in Fire-Safety Education Priorities, Preferred Method of Education, and Parent Actions

Lehna, Carlee, Janes, Erika G., Rengers, Sharon, Graviss, Jackie, Drane Scrivener, Sgt., Tom Knabel, Sgt., Myers, John A.

Journal:

Journal of Burn Care & Research

Année:

2014

Langue:

english

Fichier:

PDF, 232 KB

english, 2014

45

Quantitative Proteomics in Laser Capture Microdissected Sleep Nuclei From Rat Brain

Miller, Ronald A., Winrow, Christopher J., Spellman, Daniel S., Song, Qinghua, Reiss, Duane R., Conway, James P., Taylor, Rhonda R., Coleman, Paul J., Hendrickson, Ronald C., Renger, John J.

Journal:

Journal of Neurogenetics

Année:

2014

Langue:

english

Fichier:

PDF, 612 KB

english, 2014

46

The PDE10A inhibitor MP-10 and haloperidol produce distinct gene expression profiles in the striatum and influence cataleptic behavior in rodents

Gentzel, Renee C., Toolan, Dawn, Roberts, Rhonda, Koser, Amy Jo, Kandebo, Monika, Hershey, James, Renger, John J., Uslaner, Jason, Smith, Sean M.

Journal:

Neuropharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2015

47

Home fire safety education for parents of newborns

Lehna, Carlee, Fahey, Erin, Janes, Erika G., Rengers, Sharon, Williams, Joseph, Scrivener, Drane, Myers, John

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 325 KB

english, 2015

48

Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis

Shipe, William D., Sharik, Steven S., Barrow, James C., McGaughey, Georgia B., Theberge, Cory R., Uslaner, Jason M., Yan, Youwei, Renger, John J., Smith, Sean M., Coleman, Paul J., Cox, Christopher D.

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.35 MB

english, 2015

49

Overview of Experimental and Conventional Pharmacological Approaches in the Treatment of Sleep and Wake Disorders

Journal:

Current Topics in Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 371 KB

english, 2008

50

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

Yin, Jie, Babaoglu, Kerim, Brautigam, Chad A, Clark, Lindsay, Shao, Zhenhua, Scheuermann, Thomas H, Harrell, Charles M, Gotter, Anthony L, Roecker, Anthony J, Winrow, Christopher J, Renger, John J, Co

Journal:

Nature Structural and Molecular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2016